Awareness and uptake of genetic testing among individuals at-risk for hereditary colon cancer
نویسندگان
چکیده
Background Referral for genetic counseling and testing is appropriate for individuals whose families meet clinical criteria for Hereditary Non-Polyposis Colorectal Cancer (HNPCC) and for some families with members that meet the Bethesda criteria. The FHPP is a prospective randomized trial to evaluate an intervention to promote colonoscopy in members of high risk CRC families. FHPP participants were surveyed to assess their knowledge about and utilization of genetic testing for HNPCC.
منابع مشابه
Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome: Surveillance and Diagnostic strategies
Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation in one of four genes of the DNA mismatch repair system and increases the risk for various cancers, especially the uterine and colon cancers. The prevalence of this disease in the general population is about 1 in 500 and it causes about 2-3...
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